It has been proposed that higher protein diets more similar to the cat’s “natural diet” may be beneficial in preventing and treating obesity. Research in humans suggests that high-protein diets can help in weight management due to their effects on satiety, energy expenditure and lean body mass. Data in cats support that high-protein diets have positive effects in feline weight loss plans and in prevention of weight regain. However, there currently is no evidence that high-protein diets fed ad libitum can be helpful in preventing weight gain either by decreasing voluntary energy intake or by increasing energy expenditure.