Healing of wounds results in intensified cellular activity, which causes an increased metabolic demand for nutrients. Nutritional deficiencies can slow down wound healing but some nutrients can improve healing time and wound outcome. Nutrients known to benefit and support wound healing include Vitamins A, C and E, Bromelain, Glucosamine and adequate protein (in particular the amino acids arginine and glutamine). The botanical medicines Centella asiatica and Aloe vera have been used for many years, both topically and internally, to improve wound repair, and research is now starting to confirm their efficacy and deduce their mechanisms of action. To encourage optimal speedy wound healing with minimal pain or scarring, it is vital to explore nutritional and botanical influences on wound outcome.